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RASL11B

Gene

2 papers study it2 findings

NCBI GeneTaxon

See all 2

None of its findings points the other way.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 2 more
  • Animals2

Effects

1

Cellular senescence

upin chicken cells1

1 study

  1. RASL11B induces cellular senescence in chicken cells.

    “RASL11B overexpression was sufficient to induce aging phenotypes, confirming its central role in promoting uterine cellular aging.”

    Cellsoverexpressionuterine epithelial cells

    Integrated mRNA-seq and miRNA-seq analysis reveals miR-210a-5p regulates uterine aging in laying hens by targeting the RASL11B/Raf/MAPK pathway

    Journal of animal science and biotechnology

More on Cellular senescence

Upstream

1

miR-210a-5p

downin chicken cells1

1 study

  1. miR-210a-5p inhibits RASL11B in chicken cells.

    “Target prediction and experimental validation showed that miR-210a-5p directly suppresses the expression of RASL11B”

    Cellsin primary uterine epithelial cellsuterine epithelial cells

    Integrated mRNA-seq and miRNA-seq analysis reveals miR-210a-5p regulates uterine aging in laying hens by targeting the RASL11B/Raf/MAPK pathway

    Journal of animal science and biotechnology

More on miR-210a-5p

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