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QR2

There is 1 paper on QR2 in aging research: none in people yet, 1 in animals.

Gene

1 paper studies it2 findings

HGNCNCBI GeneTaxon

See all 1 papers on QR2

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Israel Science Foundation and 1 more
  • Animals1

Interventions

1

Novelty

downin mice1

1 study

  1. Novelty decreases QR2 in inhibitory interneurons.

    “Interestingly, novel experience decreases QR2 expression predominately in inhibitory interneurons.”

    Animalsin inhibitory interneuronsinhibitory interneuronsmales

    Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation

    The Journal of neuroscience : the official journal of the Society for Neuroscience

More on Novelty

Upstream

1

MIR-182

downin mice1

1 study

  1. MIR-182 decreases QR2 in mice (via dopamine D1 receptor activation).

    “quinone reductase 2 (QR2) is suppressed by miRNA-182 (miR-182) in the CA1 region of the hippocampus via dopamine D1 receptor (D1R) activation”

    Animalsvia dopamine D1 receptor activationhippocampal CA1 regionmales

    Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation

    The Journal of neuroscience : the official journal of the Society for Neuroscience

More on MIR-182

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