iScience
Kidney dysfunction promotes wasting and frailty signs in animals
Loss of kidney filtering units under metabolic and cardiovascular stress led to wasting independent of calorie intake, with muscle loss and frailty-like features.Loss of kidney filtering units under metabolic and cardiovascular stress led to wasting independent of calorie intake, with muscle loss and frailty-like features.
Mouse studyKidney
Who was studiedMale mice under cardiometabolic stress, against mice under stress without nephrectomy
What changedStressed mice with kidney tissue loss had less muscle, weaker grip, and poorer endurance than stressed mice without tissue loss
The catchThe exercise score includes body weight, so lighter mice can score worse without running less