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ESOX17FNV

Gene

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Cornell Center for Materials Research and 3 more
  • Cells1

Effects

1

Induced neural stem cell reprogramming

upin human cells1upin mouse cells1

1 study

  1. ESOX17FNV induces induced neural stem cell reprogramming in human cells.

    “eSox17FNV efficiently drives iNSC reprogramming while Sox2 or Sox17 fail.”

    Cells

    An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming

    Science advancesAug 23, 2023

  2. ESOX17FNV induces induced neural stem cell reprogramming in mouse cells.

    “We report iNSC reprogramming from embryonic and aged mouse fibroblasts as well as from human blood using an engineered Sox17 (eSox17FNV).”

    Cells

    An engineered Sox17 induces somatic to neural stem cell fate transitions independently from pluripotency reprogramming

    Science advancesAug 23, 2023

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