ecl1
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Japan Society for the Promotion of Science and 1 more
- Cells4
Interventions
1Magnesium depletion
upin fission yeast cells1
1 study
Magnesium depletion
upin fission yeast cells1
Magnesium depletion induces ecl1 in fission yeast cells.
“In amino acid auxotrophic strains, Mg2+ depletion robustly induces ecl1+ expression through the activation of the general amino acid control (GAAC) pathway”
Cellsin amino acid auxotrophic strains
Magnesium depletion extends fission yeast lifespan via general amino acid control activation
MicrobiologyOpen
Effects
4Lifespan
upin fission yeast1is required forin fission yeast cells1upin yeast1
2 studies
Lifespan
upin fission yeast1is required forin fission yeast cells1upin yeast1
ecl1 extends lifespan in yeast.
“Ecl1 family genes are conserved among yeast, in which their overexpression extends chronological lifespan.”
Review
Factors extending the chronological lifespan of yeast: Ecl1 family genes
FEMS yeast research
ecl1 is required for lifespan in fission yeast cells.
“this extension depends on the Ecl1-family proteins.”
Cellszinc limitation
Molecular genetics and genomics : MGG
ecl1 extends lifespan in fission yeast.
“Overexpression of Ecl1-family genes (ecl1 +, ecl2 +, and ecl3 +) results in the extension of the chronological life span in Schizosaccharomyces pombe.”
Review
Molecular genetics and genomics : MGG
mTOR signaling
downin fission yeast2
2 studies
mTOR signaling
downin fission yeast2
ecl1 inhibits mTOR signaling in fission yeast.
“These proteins also repress the target of rapamycin complex 1 (TORC1), which is conserved across eukaryotes.”
Review
Responses to nutrient starvation in the fission yeast Schizosaccharomyces pombe
Microbiological research
ecl1 inhibits mTOR signaling in fission yeast.
“Recent studies reported that Ecl family proteins strongly suppress target of rapamycin complex 1”
Review
ecl family genes: Factors linking starvation and lifespan extension in Schizosaccharomyces pombe
Molecular microbiology
Chronological lifespan
upin fission yeast1upin fission yeast cells1
2 studies
Chronological lifespan
upin fission yeast1upin fission yeast cells1
ecl1 extends chronological lifespan in fission yeast.
“ecl family genes were identified in the genomic region encoding non-coding RNA as positive regulators of CLS in S. pombe”
Review
ecl family genes: Factors linking starvation and lifespan extension in Schizosaccharomyces pombe
Molecular microbiology
ecl1 extends chronological lifespan in fission yeast cells.
“Ecl1 family genes, the overexpression of which results in the extension of CLS”
Cellsoverexpression
Molecular microbiology
Ribosome amount regulation
is required forin fission yeast cells1
1 study
Ribosome amount regulation
is required forin fission yeast cells1
ecl1 is required for ribosome amount regulation in fission yeast cells.
“expression of Ecl1 family genes was required for regulating ribosome amount when cells were starved”
Cellswhen cells were starved
Magnesium depletion extends fission yeast lifespan via general amino acid control activation
MicrobiologyOpen
Upstream
1zip1
upin fission yeast cells1
1 study
zip1
upin fission yeast cells1
zip1 activates ecl1 in fission yeast cells.
“Zip1 transcription factor results in the sulfur restriction-dependent expression of the ecl1+ gene”
Cellssulfur restriction
Molecular microbiology