There are 3 papers on DOCK4 in aging research: 2 observational studies in people, 1 in animals.
At a glance
The findings reach mice, none yet in people. 1 lab in 1 country.
Mice: a single group. Cells, worms or flies and humans: nothing yet.
- 1 lab in 1 country
- Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 3 more
- Humans2
- Animals1
Effects
1Mature neurons
upin mice1
1 study
Mature neurons
upin mice1
DOCK4 increases mature neurons in mice (shown by knockout).
“dock4 deficiency led to decreased mature neurons and oligodendrocytes but increased astrocytes in the hippocampus of late-middle-aged mice.”
Animalsshown by knockouthippocampusmales
Cellular and molecular neurobiology
Latest
2 papers in 12 monthsmedRxiv
Genome wide association study meta-analysis of neuropathologic lesions of Alzheimer's disease and related dementias in a multi-site autopsy cohort
Preprint: genetic association study of 12,509 peopleMechanisms
HGG Advances
Large-scale blood pressure GWAS accounting for gene-depression interactions in 564,680 individuals from diverse populations
Study of 564,680 peopleDepression
Cellular and Molecular Neurobiology
Deficiency of Autism-Related Gene Dock4 Leads to Impaired Spatial Memory and Hippocampal Function in Mice at Late Middle Age
Experiments in miceMechanisms