dAnkmy2

Gene

1 paper4 findings

Taxon

  • 1 lab in 1 country
  • Funder: Japan Society for the Promotion of Science
  • Model organisms1

Effects

4

Larval survival

is required forin flies1

1 study
  1. dAnkmy2 is required for larval survival in flies.

    “In contrast, loss of dAnkmy2 caused larval lethality, indicating an essential developmental function.”

    Model organismsshown by loss of dAnkmy2

    A gain-of-function screening reveals dAnkmy2 as a potential mediator of lifespan extension and oxidative stress resistance in Drosophila melanogaster

    Biogerontology26 Apr 2026

Canonical antioxidant gene expression

no changein flies1

1 study
  1. dAnkmy2 has no effect on canonical antioxidant gene expression in flies.

    “Overexpression of dAnkmy2 significantly extended adult lifespan and enhanced resistance to oxidative stress without detectable changes in canonical antioxidant gene expression.”

    Model organismsdAnkmy2 overexpression

    A gain-of-function screening reveals dAnkmy2 as a potential mediator of lifespan extension and oxidative stress resistance in Drosophila melanogaster

    Biogerontology26 Apr 2026

More on Canonical antioxidant gene expression

Oxidative stress resistance

upin flies1

1 study
  1. dAnkmy2 increases oxidative stress resistance in flies.

    “Overexpression of dAnkmy2 significantly extended adult lifespan and enhanced resistance to oxidative stress without detectable changes in canonical antioxidant gene expression.”

    Model organismsdAnkmy2 overexpression

    A gain-of-function screening reveals dAnkmy2 as a potential mediator of lifespan extension and oxidative stress resistance in Drosophila melanogaster

    Biogerontology26 Apr 2026

Adult lifespan

upin flies1

1 study
  1. dAnkmy2 extends adult lifespan in flies.

    “Overexpression of dAnkmy2 significantly extended adult lifespan and enhanced resistance to oxidative stress without detectable changes in canonical antioxidant gene expression.”

    Model organismsdAnkmy2 overexpression

    A gain-of-function screening reveals dAnkmy2 as a potential mediator of lifespan extension and oxidative stress resistance in Drosophila melanogaster

    Biogerontology26 Apr 2026

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