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CXCL4

Gene

1 paper studies it2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funders: Australian Government and 8 more
  • Animals1

Effects

2

Hippocampal neurogenesis

upin mice1

1 study

  1. CXCL4 improves hippocampal neurogenesis in mice.

    “increasing the systemic levels of the platelet-derived exerkine CXCL4/platelet factor 4 (PF4) ameliorates age-related regenerative and cognitive impairments”

    Animalshippocampal neurogenesis-dependenthippocampus

    Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

    Nature communications

Cognitive function

upin mice1

1 study

  1. CXCL4 improves cognitive function in mice.

    “increasing the systemic levels of the platelet-derived exerkine CXCL4/platelet factor 4 (PF4) ameliorates age-related regenerative and cognitive impairments”

    Animalshippocampal neurogenesis-dependentbrain

    Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice

    Nature communications

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