Renal Failure
Gut microbe-derived compound promotes kidney aging in mice
Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.Reducing a circular RNA weakened the compound’s effects in male mice given it in drinking water for 16 weeks.
Mouse studyKidney
Who was studiedMale C57BL/6J mice, 16 weeks, against control mice
What changedKidney aging markers were higher in TMAO-treated mice than in control mice
The catchOnly 4 mice per group contributed to the kidney senescence analyses