br

1. br is required for intestinal injury repair in flies.

   “Here, this study demonstrates that br is required for the maintenance of intestinal stem cells (ISCs) and intestinal injury repair.”

   Model organismsintestinal injuryintestine

   Role of broad in intestinal stem cells of adult Drosophila

   Yi chuan = Hereditas·1 Jun 2026

1. br activates JAK–STAT signalling in flies.

   “Further analysis reveals that br knockdown reduces Jak/STAT signaling activity in ISCs.”

   Model organismsknockdownintestine

   Role of broad in intestinal stem cells of adult Drosophila

   Yi chuan = Hereditas·1 Jun 2026

More on JAK–STAT signalling

1. br improves stem cell differentiation in flies.

   “Knockdown of br severely impairs the differentiation of stem cells into enterocytes (ECs), whereas overexpression of br promotes ECs differentiation.”

   Model organismsknockdownintestine

   Role of broad in intestinal stem cells of adult Drosophila

   Yi chuan = Hereditas·1 Jun 2026

More on Stem cell differentiation