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BDNFMETALLELE

There is 1 paper on BDNFMETALLELE in aging research: 1 observational study in people.

Gene

1 paper studies it1 finding

See all 1

“BDNF polymorphism was associated with larger dentate gyrus volumes within the anterior hippocampus (head) in Met-carriers compared to Val/Val homozygotes.”
The associations of the BDNF and APOE polymorphisms, hippocampal subfield volumes, and episodic memory performance across the lifespanHippocampus2020doi:10.1002/hipo.23217

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Funder: Gouvernement du Canada | Canadian Institutes of Health Research
  • Humans1

Effects

1

Dentate gyrus volume

upin humans1

1 study

  1. BDNFMETALLELE is linked with higher dentate gyrus volume in humans (anterior hippocampus (head); Met-carriers compared with Val/Val homozygotes).

    “BDNF polymorphism was associated with larger dentate gyrus volumes within the anterior hippocampus (head) in Met-carriers compared to Val/Val homozygotes.”

    Humansanterior hippocampus (head); Met-carriers compared with Val/Val homozygotesanterior hippocampusn = 127

    The associations of the BDNF and APOE polymorphisms, hippocampal subfield volumes, and episodic memory performance across the lifespan

    Hippocampus

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