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ADE8

Gene

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Includes the processes named after it and trials of drugs aimed at it.

  • 1 lab in 1 country
  • Cells1

Effects

1

Chronological lifespan extension

is required forin S. paradoxus cells1

1 study

  1. ADE8 is required for chronological lifespan extension in S. paradoxus cells.

    “Deletion of ADE8, NCS2, or TRM9 prevented lifespan extension”

    CellsRequired for Ty1-associated lifespan extension under hydroxyurea exposure, shown by ADE8 deletionmoderate dose of hydroxyurea; quantity not stated

    Lifespan Extension by Retrotransposons under Conditions of Mild Stress Requires Genes Involved in tRNA Modifications and Nucleotide Metabolism

    International journal of molecular sciences1 Oct 2024

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