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Prolonged critical illness

Disease

1 paper studies it3 findings

  • Humans1

Effects

3

Ki-67 proliferation index

upin humans1

1 study

  1. Prolonged critical illness increases Ki-67 proliferation index in humans (P = 0.0039 for men and P = 0.0063 for women).

    “The Ki-67 proliferation index in ZR cells was higher in the PCI group than in the control group (P = 0.0039 for men and P = 0.0063 for women).”

    Humanspost-mortem autopsyadrenal zona reticularis

    Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness

    Frontiers in endocrinologySep 4, 2023

More on Ki-67 proliferation index

ZR cell count

upin humans1

1 study

  1. Prolonged critical illness increases ZR cell count in humans (P < 0.0001 for both men and women).

    “The number of ZR cells was higher in the PCI group than in the control group for both men and women (P < 0.0001 for both men and women).”

    Humanspost-mortem autopsyadrenal zona reticularis

    Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness

    Frontiers in endocrinologySep 4, 2023

More on ZR cell count

Relative telomere length

downin humans1

1 study

  1. Prolonged critical illness decreases relative telomere length in humans (P = 0.0001 for men and P = 0.0012 for women).

    “RTLs in ZR cells were significantly shorter in the PCI group than in the control group for both men and women (P = 0.0001 for men and P = 0.0012 for women).”

    Humanspost-mortem autopsyadrenal zona reticularis

    Accelerated telomere shortening in adrenal zona reticularis in patients with prolonged critical illness

    Frontiers in endocrinologySep 4, 2023

More on Relative telomere length

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