Progression to CKM stage 4

Disease

1 paper2 findings

  • Humans1

Associations

2

Elevated TyG and reduced NCCR

upin humans1

1 study
  1. Elevated TyG and reduced NCCR is associated with progression to CKM stage 4 in humans.

    Humansjoint exposure analysis

    Combined blood marker linked to cardiovascular disease risk

    Cardiovascular diabetology9 Oct 2026

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TyG-NCCR

upin humans1HR 1.2

1 study
  1. TyG-NCCR predicts progression to CKM stage 4 in humans (HR 1.20 per SD increase, 95% CI 1.13–1.29).

    HumansCHARLS participants with CKM stages 0–3 at baseline; adjusted Cox modelseach SD increase2011 to 2020n = 5,474

    Combined blood marker linked to cardiovascular disease risk

    Cardiovascular diabetology9 Oct 2026

More on TyG-NCCR

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Cardiovascular Diabetology

Combined blood marker linked to cardiovascular disease risk

An observational study followed 5,474 Chinese participants from 2011 to 2020 and linked higher marker values to progression to clinical cardiovascular disease.An observational study followed 5,474 Chinese participants from 2011 to 2020 and linked higher marker values to progression to clinical cardiovascular disease.

Cohort study of 5,474 peopleCardiovascular disease