Mild autonomous cortisol secretion

1. Mild autonomous cortisol secretion is associated with cardiovascular disease in humans.

   “MACS is related to increased CVD prevalence”

   Humansin patients with adrenal adenomas

   Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal adenomas only in the presence of type 2 diabetes: a retrospective cohort study · Cardiovascular diabetology · 22 Sep 2026

Cardiovascular disease →

1. Mild autonomous cortisol secretion is associated with mortality in humans (HR 2.51 [CI95% 1.41-4.48]).

   “MACS was strongly linked to increased mortality only in T2D (HR 2.51 [CI95% 1.41-4.48], p”

   Humansin patients with type 2 diabetes and adrenal adenomas compared to non-functioning adrenal adenomas without type 2 diabetes

   Mild autonomous cortisol secretion (MACS) is associated with increased mortality in patients with adrenal adenomas only in the presence of type 2 diabetes: a retrospective cohort study · Cardiovascular diabetology · 22 Sep 2026