KSHV infection
1 paper4 findings
- Cells1
Interventions
1Recombinant human CD109
downin human cells1
1 study
Recombinant human CD109
downin human cells1
Recombinant human CD109 inhibits KSHV infection in human cells.
“recombinant CD109 protein exhibiting inhibitory activity of KSHV infection by blocking virion binding.”
Cellsrecombinant protein
The Journal of clinical investigationDec 12, 2024
Associations
3CAV1
upin human cells1
1 study
CAV1
upin human cells1
CAV1 raises the risk of KSHV infection in human cells.
“we identified caveolin-1 and CD109 as host factors significantly upregulated in senescent cells that promote KSHV infection.”
Cellsendothelial cells
The Journal of clinical investigationDec 12, 2024
CD109
upin human cells1
1 study
CD109
upin human cells1
CD109 raises the risk of KSHV infection in human cells.
“we identified caveolin-1 and CD109 as host factors significantly upregulated in senescent cells that promote KSHV infection.”
Cellsendothelial cells
The Journal of clinical investigationDec 12, 2024
Cellular senescence
upin human cells1
1 study
Cellular senescence
upin human cells1
Cellular senescence raises the risk of KSHV infection in human cells.
“This study uncovered a link between cellular senescence and enhanced KSHV infectivity in human endothelial cells.”
Cellsendothelial cells
The Journal of clinical investigationDec 12, 2024
Latest
The Journal of Clinical Investigation
Senescence of endothelial cells increases susceptibility to Kaposi's sarcoma-associated herpesvirus infection via CD109-mediated viral entry
Experiments in human cellsCellular senescence
PLOS Pathogens
KSHV requires vCyclin to overcome replicative senescence in primary human lymphatic endothelial cells
Experiments in cellsMechanisms
bioRxiv
PDGFRA Defines the Mesenchymal Stem Cell Kaposi’s Sarcoma Progenitors by Enabling KSHV Oncogenesis in an Angiogenic Environment
Preprint: experiments in cellsMechanisms