Incident metabolic dysfunction-associated steatotic liver disease

Disease

1 paper1 finding

Humans1

Associations

Weight loss

downin humans1HR 0.9

1 study

Weight loss is associated with incident metabolic dysfunction-associated steatotic liver disease in humans (HR 0.90 [0.89–0.91] per 1% weight reduction).
HumansParticipants without MASLDEach 1% reduction in body weightMedian follow-up of 4 yearsn = 11,882
Weight changes differentially impact MASLD incidence, progression and outcomes based on genetic and metabolic risk profiles
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association9 Oct 2026

Latest

3 in 12 months

Clinical Gastroenterology and Hepatology2 h

Weight changes differentially impact MASLD incidence, progression and outcomes based on genetic and metabolic risk profiles

Cohort study of 11,882 peoplePopulations

Paper

Hepatology International7 Oct

Blood proteins linked aging measures to fatty liver disease risk

Blood proteins statistically accounted for 0.5 to 50.7% of the risk associated with biological aging measures.Blood proteins statistically accounted for 0.5 to 50.7% of the risk associated with biological aging measures.

Cohort study of 52,131 peopleMechanisms

Paper

Frontiers in Nutrition10 Sep

Circulating metabolite signatures mediating the association between minerals in domestic water and incident MASLD: a prospective cohort study

Cohort study of 218,339 peoplePopulations

Paper

Incident metabolic dysfunction-associated steatotic liver disease

Associations

Latest

Weight changes differentially impact MASLD incidence, progression and outcomes based on genetic and metabolic risk profiles

Blood proteins linked aging measures to fatty liver disease risk

Circulating metabolite signatures mediating the association between minerals in domestic water and incident MASLD: a prospective cohort study

Related