Hypertensive renal disease

2 papers study it2 more mention it2 findings

Humans1
Animals1

Effects

1

Mortality

upin humans1

1 study

Hypertensive renal disease increases mortality in humans (APC 9.75% (95% CI: 7.87–11.67), AAMR from 5.28 to 29.60).
“From 1999 to 2020, a total of 618,157 deaths occurred from HRD in adults. AAMR started from 5.28 in 1999 and ended at 29.60 in 2020 (Total AAMR: 12.93) [APC: 9.75 (95% CI: 7.87–11.67)].”
Humans1999 to 2020n = 618,157
Unseen and Unstoppable: The Burden of Hypertensive Renal Disease in the U.S. - A 22-Year Mortality Analysis (1999–2020)
AHA Scientific Sessions 2025 abstractNov 3, 2025

Upstream

1

ATP1A1

downin rats1

1 study

ATP1A1 decreases hypertensive renal disease in rats.
“Transgenic Dahl S rats exhibited less salt-sensitive hypertension, less hypertensive renal disease, and longer life span when compared with non-transgenic Dahl S controls.”
Animalsin transgenic Dahl S rats bearing Dahl R wild-type alpha1 Na,K-ATPase cDNA
The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitiveHSD rat
The Journal of clinical investigationSep 15, 1998

Latest

1 paper in 12 months

AHA Scientific Sessions 2025 AbstractNov 3

Unseen and Unstoppable: The Burden of Hypertensive Renal Disease in the U.S. - A 22-Year Mortality Analysis (1999–2020)

Cohort study of 618,157 peopleKidney

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Study in peopleBiomarkers

The Journal of Clinical InvestigationSep 15

The alpha1 Na,K-ATPase gene is a susceptibility hypertension gene in the Dahl salt-sensitiveHSD rat

Experiments in ratsHypertension