3 findings
Cerebral amyloid angiopathy
no changein humans1
Extracranial carotid atherosclerotic disease has no effect on cerebral amyloid angiopathy in humans.
“In contrast to NFT, ECAD was not associated with beta-amyloid plaques or CAA density.”
Humansbrain
Journal of vascular surgery31 Aug 2021
Beta-amyloid plaques
no changein humans1
Extracranial carotid atherosclerotic disease has no effect on beta-amyloid plaques in humans.
“In contrast to NFT, ECAD was not associated with beta-amyloid plaques or CAA density.”
Humansbrain
Journal of vascular surgery31 Aug 2021
Neurofibrillary tangles
upin humans1+21%
Extracranial carotid atherosclerotic disease is associated with neurofibrillary tangles in humans (+21%).
“We found that the presence of ECAD was associated with a 21% greater NFT burden at death compared with no ECAD (P = .02).”
Humansbrain
Journal of vascular surgery31 Aug 2021
In adults with asymptomatic carotid disease, hypertension was linked to lower Alzheimer's disease risk (HR = 0.56) and higher cognitive scores (β = 0.47).In adults with asymptomatic carotid disease, hypertension was linked to lower Alzheimer's disease risk (HR = 0.56) and higher cognitive scores (β = 0.47).