Detrusor underactivity
2 papers2 findings
Associations
2Metabolic syndrome
upin animal1
1 study
Metabolic syndrome
upin animal1
Metabolic syndrome raises the risk of detrusor underactivity in animal.
“detrusor underactivity-like phenotypes have been observed at a relatively early age in animal models with metabolic syndrome”
Review
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshiJan 1, 2024
Diabetes mellitus
upin animal1
1 study
Diabetes mellitus
upin animal1
Diabetes mellitus raises the risk of detrusor underactivity in animal.
“bladder dysfunction resulting from detrusor underactivity is observed at an earlier age in animal models with diabetes mellitus than in those without.”
Review
Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshiJan 1, 2024
Funding
1 grant since 2021National Institute on AgingUS$1.2m
Latest
1 in 12 monthsJournal of Smooth Muscle Research
Association of detrusor underactivity with aging and metabolic syndrome: suggestions from animal models
ReviewMechanisms
Biogerontology
Loss of resilience contributes to detrusor underactivity in advanced age
Experiments in animalsMechanisms
Life Sciences
Role of hyperpolarization-activated cyclic nucleotide-gated channels in aging bladder phenotype
Experiments in animalsMechanisms
Life Sciences
Aging-related severe hypertension induces detrusor underactivity in rats
Experiments in animalsMechanisms
American Journal of Clinical and Experimental Urology
Micturition defects and altered bladder function in the klotho mutant mouse model of aging
Experiments in animalsMechanisms
Lower Urinary Tract Symptoms
Underactive bladder in aging rats is associated with a reduced number of serotonin-expressing cells in the urethra and is improved by serotonin application to the urethra
Experiments in animalsMechanisms