Degenerative spinal diseases

1 paper1 finding

Associations

1

Systemic aging

upin humans1

1 study

systemic aging raises the risk of degenerative spinal diseases in humans.
“spinal degeneration is not an isolated local event, but is influenced by systemic aging through a multi-organ aging network.”
Review
From local to systemic: Spinal aging in the multi-organ aging network
Ageing research reviews11 Jul 2026

Latest

2 in 12 months

Ageing Research Reviews12 Jul

From local to systemic: Spinal aging in the multi-organ aging network

ReviewMechanisms

Aging Cell20 Mar

FGF21-Mediated Upregulation of SIRT1 Delays Intervertebral Disc Degeneration by Promoting PINK1/Parkin Dependent Mitophagy Through Deacetylation of FOXO3

Experiments in ratsIntervertebral disc degeneration

The Spine Journal8 Apr

Accelerated biological aging in patients with degenerative spine diseases: the impact of modifiable lifestyle factors on phenotypic age

Study in peopleBiomarkers

Molecular Medicine30 Mar

Sirtuins in intervertebral disc degeneration: current understanding

Systematic reviewSirtuin signalling