JCI Insight
Gene variants made human blood-forming cells stop dividing early
In experiments with human blood-forming cells, an additional mutation reduced the defects caused by one inherited variant.In experiments with human blood-forming cells, an additional mutation reduced the defects caused by one inherited variant.
Human cell studyMechanisms
Who was studiedHuman blood-forming stem and precursor cells
What changedHuman blood-forming stem and precursor cells carrying inherited SEPT6 variants stopped dividing earlier