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Chronic ulcerative dermatitis

Disease

1 paper2 findings

  • Animals1

Interventions

1

Radiation

upin mice1downin mice1

1 study

  1. Radiation increases chronic ulcerative dermatitis in mice.

    “chronic, fractionated exposure for 30 or 60 weeks significantly increased the frequency and severity of the disease in older Trp53+/- mice”

    Animalsin Trp53+/- mice48 or 97 mGy (0.33 mGy/day, 0.7 mGy/h)30 or 60 weeksfemales

    Fractionated, low-dose-rate ionizing radiation exposure and chronic ulcerative dermatitis in normal and Trp53 heterozygous C57BL/6 mice

    Radiation research1 Dec 2007

  2. Radiation decreases chronic ulcerative dermatitis in mice.

    “The 90-week exposure produced an adaptive response, decreasing both disease frequency and severity in Trp53+/+ mice”

    Animalsin Trp53+/+ mice146 mGy (0.33 mGy/day, 0.7 mGy/h)90 weeksfemales

    Fractionated, low-dose-rate ionizing radiation exposure and chronic ulcerative dermatitis in normal and Trp53 heterozygous C57BL/6 mice

    Radiation research1 Dec 2007

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