Papers on age-related neuropathologies

70 papers1 new in 30 days

Sunday, May 14

AgingMay 14

Proteostatic modulation in brain aging without associated Alzheimer's disease-and age-related neuropathological changes

Cross-sectional study in peopleProteostasis

Paper

Friday, April 21

Brain CommunicationsApr 21

Multi-omic integration via similarity network fusion to detect molecular subtypes of ageing

Cohort study of 513 peoplePopulations

Paper

Thursday, November 17

bioRxivNov 17

Multi-‘Omic Integration via Similarity Network Fusion to Detect Molecular Subtypes of Aging

Preprint: cohort study of 513 peoplePopulations

Paper

Monday, October 3

Psychiatry and Clinical NeurosciencesOct 3

Towards an understanding of the pathological basis of senile depression and incident dementia: Implications for treatment

ReviewMechanisms

Paper

Saturday, June 11

International Journal of Molecular SciencesJun 11

Blood-Brain Barrier Dysfunction and Astrocyte Senescence as Reciprocal Drivers of Neuropathology in Aging

ReviewCellular senescence

Paper

Tuesday, March 22

Alzheimer's & DementiaMar 22

Early Alzheimer's disease-like reductions in gray matter and cognitive function with aging in nonhuman primates

Experiments in 48 monkeysMechanisms

Paper

Saturday, March 19

Frontiers in Aging NeuroscienceMar 19

Exosomes in Age-Related Cognitive Decline: Mechanistic Insights and Improving Outcomes

ReviewMechanisms

Paper

Monday, February 21

Behavioural Brain ResearchFeb 21

Age-related deficits in working memory in 5xFAD mice in the Hebb-Williams maze

Experiments in miceMechanisms

Paper

Tuesday, January 11

Neurobiology of AgingJan 11

Relationship between regional white matter hyperintensities and alpha oscillations in older adults

Cohort study of 907 peopleMechanisms

Paper

Wednesday, July 7

Handbook of Clinical NeurologyJul 7

Spatial topography of the basal forebrain cholinergic projections: Organization and vulnerability to degeneration

ReviewMechanisms

Paper

Sunday, March 21

BrainMar 21

To what degree is late life cognitive decline driven by age-related neuropathologies?

Cohort study of 1,164 peopleMechanisms

Paper

Sunday, March 7

Aging CellMar 7

Functional genomic analyses highlight a shift in Gpr17-regulated cellular processes in oligodendrocyte progenitor cells and underlying myelin dysregulation in the aged mouse cerebrum

Experiments in miceMechanisms

Paper

Thursday, January 14

PreprintJan 14

Adropin expression correlates with age-related neuropathologies in the human brain and improves neuroinflammation and cognitive function in aging mice

Preprint: experiments in miceInterventions

Paper

Thursday, November 5

GigaByteNov 5

The first Antechinus reference genome provides a resource for investigating the genetic basis of semelparity and age-related neuropathologies

Experiments in animalsAI & data

Paper

Sunday, September 6

bioRxivSep 6

Relationship between Regional White Matter Hyperintensities and Alpha Oscillations in Older Adults

Preprint: cross-sectional study of 907 peopleMechanisms

Paper

Saturday, August 8

StrokeAug 8

Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults

Study in peopleBiomarkers

Paper

Thursday, July 2

JAMA PsychiatryJul 2

Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons

Cohort study of 391 peopleMechanisms

Paper

Wednesday, May 27

Alzheimer Disease and Associated DisordersMay 27

Limbic-predominant Age-related TDP-43 Encephalopathy and Distinct Longitudinal Profiles of Domain-specific Literacy

Study in peoplePopulations

Paper

Thursday, November 28

Journal of Alzheimer's DiseaseNov 28

Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults

Study in peopleBiomarkers

Paper

Tuesday, October 1

Annals of Clinical and Translational NeurologyOct 1

Common age-related neuropathologies and yearly variability in cognition

Study in peopleMechanisms

Paper

Tuesday, May 21

Frontiers in Aging NeuroscienceMay 21

Gi/o-Protein Coupled Receptors in the Aging Brain

ReviewMechanisms

Paper

Wednesday, May 8

Human Brain MappingMay 8

A longitudinal characterization of perfusion in the aging brain and associations with cognition and neural structure

Cohort study of 161 peopleMechanisms

Paper

Thursday, May 2

Frontiers in Molecular NeuroscienceMay 2

Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

Experiments in fliesNRF2–KEAP1 antioxidant response

Paper

Monday, April 1

DNA RepairApr 1

Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population

Genetic association study of 3,730 peoplePopulations

Paper

Tuesday, March 19

Journal of Alzheimer's DiseaseMar 19

An UNC5C Allele Predicts Cognitive Decline and Hippocampal Atrophy in Clinically Normal Older Adults

Study in peoplePopulations

Paper

Thursday, February 21

Neurobiology of AgingFeb 21

Associations of amygdala volume and shape with transactive response DNA-binding protein 43 (TDP-43) pathology in a community cohort of older adults

Study in peopleMechanisms

Paper

Wednesday, February 6

Frontiers in NeurologyFeb 6

Tonic Neuromuscular Processing Affects Postural Adaptation Differently in Aging and Parkinson's Disease

Cross-sectional study of 41 peopleMechanisms

Paper

Wednesday, November 14

Annals of NeurologyNov 14

Attributable risk of Alzheimer's dementia attributed to age-related neuropathologies

Study in peoplePopulations

Paper

Sunday, August 26

Neurobiology of AgingAug 26

Resting-state EEG power and connectivity are associated with alpha peak frequency slowing in healthy aging

Cross-sectional study in peopleMechanisms

Paper

Sunday, June 17

Neurobiology of AgingJun 17

Postmortem brain MRI is related to cognitive decline, independent of cerebral vessel disease in older adults

Study in peopleBiomarkers

Paper