Acquired aplastic anemia

Acquired aplastic anemia is associated with selective expansion of multipotent PIGA-mutant stem/progenitor cells in humans.

“Those in acquired aplastic anemia reflect the selective expansion of multipotent PIGA-mutant stem/progenitor cells across myeloid and lymphoid lineages.”

Humansmyeloid and lymphoid lineages

The origins of rare glycosylphosphatidylinositol-deficient cells in normal and immune-mediated hematopoiesis

Blood·7 Oct 2026