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White matter lesion burden

Biomarker

1 paper2 findings

  • Humans1

Effects

1

Oxygen supply

no changein humans1

1 study

  1. White matter lesion burden has no effect on oxygen supply in humans (p = 0.87).

    “despite no differences in oxygen supply between these subgroups (p = 0.87).”

    Humansin low vascular risk subgroup

    Cerebral microvascular physiology associated with white matter lesion burden differs by level of vascular risk in typically aging older adults

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismNov 20, 2024

More on Oxygen supply

Associations

1

Oxygen extraction fraction

downin humans1

1 study

  1. White matter lesion burden is associated with oxygen extraction fraction in humans (p = 0.02).

    “In the low vascular risk subgroup, OEF was uniquely lower in the individuals with high WML versus low WML burden (p = 0.02)”

    Humansin low vascular risk subgroup

    Cerebral microvascular physiology associated with white matter lesion burden differs by level of vascular risk in typically aging older adults

    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and MetabolismNov 20, 2024

More on Oxygen extraction fraction

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