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White matter brain age gap

Biomarker

1 paper1 finding

  • Humans1

Associations

1

Life's essential 8

downin humans1

1 study

  1. Life's essential 8 is associated with white matter brain age gap in humans (124 days younger per 10-point increase (95% CI: 102–146 days)).

    “The effect was more pronounced in non-APOE4 carriers (124 days younger per 10-point increase, 95% CI: 102-146 days; p < 0.001)”

    Humansnon-APOE4 carrierswhite matter10-point increase in LE8 score

    Adherence to life's essential 8 is associated with delayed white matter aging

    EBioMedicine24 Apr 2025

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