Weighted LDL-C gene score

Biomarker

1 paper2 findings

  • Humans1

Upstream

1

Familial hypercholesterolaemia

upin humans1

1 study
  1. Familial hypercholesterolaemia increases weighted LDL-C gene score in humans (1.0 [SD 0.21] vs 0.90 [SD 0.23], p=4.5 x 10(-16)).

    Humansmutation-negative familial hypercholesterolaemia

    Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

    Lancet (London, England)22 Feb 2013

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Associations

1

LDL-C

upin humans1

1 study
  1. Weighted LDL-C gene score is associated with LDL-C in humans (R(2)=0.11, p=1.4 x 10(-77)).

    Humansplasma-serum

    Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study

    Lancet (London, England)22 Feb 2013

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