Transverse relaxation rate

Biomarker

2 papers4 findings

  • Humans2

Associations

4

Gait speed

downin humans1

1 study
  1. Transverse relaxation rate is associated with gait speed in humans.

    “only SN-1 and SN-4 were associated with change in motor functioning, specifically gait speed, over time”

    Humansn = 1,239

    Sub-Networks of the Brain R₂ Structural Connectome Integrity Matrix (SCIM) and Older Adult Cognitive and Motor Functioning

    Human brain mapping1 Mar 2026

Global motor function

downin humans1

1 study
  1. Transverse relaxation rate is associated with global motor function in humans.

    “Nearly all Sub-Networks negatively associated with global motor function, dexterity and gait speed at baseline”

    Humansn = 1,239

    Sub-Networks of the Brain R₂ Structural Connectome Integrity Matrix (SCIM) and Older Adult Cognitive and Motor Functioning

    Human brain mapping1 Mar 2026

Global cognition

downin humans1

1 study
  1. Transverse relaxation rate is associated with global cognition in humans.

    “associations of lower R2 in SN-1, SN-2, and SN-4 with lower baseline global cognition”

    Humansn = 1,239

    Sub-Networks of the Brain R₂ Structural Connectome Integrity Matrix (SCIM) and Older Adult Cognitive and Motor Functioning

    Human brain mapping1 Mar 2026

Cognitive function

upin humans1

1 study
  1. Transverse relaxation rate is associated with cognitive function in humans (p-values <= 0.045).

    “demonstrated associations of higher R 2 in Sub‐Networks 1, 2, and 4 with higher cognition at baseline ( p ‐values ≤0.045)”

    Humansolder adultsbrain

    Derivation of a structural connectome integrity matrix based on the complex neural circuitry of the aging brain: A multi‐modal perspective applied to cognitive aging

    AAIC 2025 abstract23 Dec 2025

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