Total N-acetyl aspartate

Healthy aging decreases total N-acetyl aspartate in humans.

“We also found a decline in tNAA and an increase in tCr with increasing age.”

Humanscalcarine cortexn = 187

Neurochemical changes in GABA+, Glx, and the excitatory/inhibitory ratio in the calcarine cortex with healthy aging

NeuroImage·5 Dec 2025