TMEM106B filaments

1. Older age is associated with TMEM106B filaments in humans.

   “The identification of TMEM106B filaments in the brains of older, but not younger, individuals with normal neurology indicates that they form in an age-dependent manner.”

   Humansnormal neurologybrain

   Age-dependent formation of TMEM106B amyloid filaments in human brains

   Nature·Mar 28, 2022

1. TMEM106B filaments are associated with 29-kDa sarkosyl-insoluble TMEM106B fragment in humans.

   “TMEM106B filaments correlated with the presence of a 29-kDa sarkosyl-insoluble fragment and globular cytoplasmic inclusions”

   Humansbrain

   Age-dependent formation of TMEM106B amyloid filaments in human brains

   Nature·Mar 28, 2022

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