Tissue-specific epigenetic clock

1 paper2 findings

In silico1

Effects

1

Clock performance

upin silico1

1 study

Tissue-specific epigenetic clock improves clock performance in silico.
“tissue specific clocks appear to perform better than generic blood clocks”
In silico
Where are we in the implementation of tissue-specific epigenetic clocks?
Frontiers in bioinformatics4 Mar 2024

Associations

1

epigenetic aging

upin rhesus monkeys1

1 study

Tissue-specific epigenetic clock is associated with epigenetic aging in rhesus monkeys.
“tissue-specific epigenetic clocks showed that epigenetic aging was relatively consistent within individuals.”
Animals14 tissues
Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques
Science (New York, N.Y.)18 Jun 2026

Latest

4 in 12 months

Epigenetics11 Sep

A breast tissue-specific epigenetic clock provides accurate chronological age predictions and reveals de-correlation of age and DNA methylation in tumor-adjacent and tumor samples

Study of 553 peopleBiomarkers

GeroScience9 Jul

Age-associated DNA methylation patterns in mouse blood and tail: feasibility of tissue-specific epigenetic clock development

Experiments in miceEpigenetic clock

Science18 Jun

Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques

Experiments in 237 monkeysMechanisms

PNAS10 Mar

Histone modification clocks for robust cross-species biological age prediction and elucidating senescence regulation

Experiments in cellsBiomarkers

bioRxiv12 Aug

Age and early life adversity shape heterogeneity of the epigenome across tissues in macaques

Preprint: experiments in 237 monkeysMechanisms

International Journal of Molecular Sciences14 Sep

Prediction of Multiple Degenerative Diseases Based on DNA Methylation in a Co-Physiology Mechanisms Perspective

Computational studyAI & data

Frontiers in Bioinformatics19 Mar

Where are we in the implementation of tissue-specific epigenetic clocks?

Computational studyBiomarkers

Nature Aging11 Jan

TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction

Study of 1,800 peopleEpigenetic clock

bioRxiv28 Oct

TIME-Seq Enables Scalable and Inexpensive Epigenetic Age Predictions

Preprint: study in peopleBiomarkers