Thyroid-stimulating hormone

1. Thyroid-stimulating hormone mediates mild cognitive impairment in humans (10.23% (ACME OR = 1.012, 95% CI: 1.002-1.022)).

   Humansmediating association of 24 h-UIE with MCI

   Biofluid iodine concentrations are associated with mild cognitive impairment: The potential mediating role of thyroid hormones · Clinica chimica acta; international journal of clinical chemistry · 21 Sep 2026

Mild cognitive impairment →

1. Thyroid-stimulating hormone increases annual decline in eGFR in humans (0.353 (0.108, 0.598) ml/min/1.73 m2 per 1 log-odds higher exposure).

   Humansin CKD population

   Disease progression Mendelian randomization of risk factors for kidney function decline in chronic kidney disease and the general population · medRxiv · 8 Sep 2026 · Preprint

1. Thyroid-stimulating hormone is associated with cognitive function in humans.

   Humanscross-sectional population study

   Biofluid iodine concentrations are associated with mild cognitive impairment: The potential mediating role of thyroid hormones · Clinica chimica acta; international journal of clinical chemistry · 21 Sep 2026

1. Thyroid-stimulating hormone raises the risk of type 2 diabetes in humans (OR 2.82, 95% CI 1.26-6.32).

   Humanshigh TSH levelsn = 4,910

   Age- and sex-specific associations between thyroid function and diabetes in Korean adults: A nationwide cross-sectional study · Medicine · 18 Sep 2026

Type 2 diabetes →