Thyroid peroxidase antibodies

Biomarker1 paper2 findings

  • Humans1

Effects

1

Incident cardiovascular disease

no changein humans1

1 study
  1. Thyroid peroxidase antibodies have no effect on incident cardiovascular disease in humans (Adjusted HR per 1-SD increase: 1.04, 95% CI 0.95–1.13).

    HumansWithout baseline cardiovascular disease; adjusted analysis per 1-SD increase14.8 ± 3.3 years after landmark56.5% femalesn = 4,825

    Thyroid antibodies linked to heart risk in younger adults · Journal of translational autoimmunity · 22 Sep 2026

Incident cardiovascular disease →

Associations

1

Incident cardiovascular disease

upin humans1HR 1.35

1 study
  1. Thyroid peroxidase antibodies are associated with incident cardiovascular disease in humans (Adjusted HR 1.35, 95% CI 1.10–1.66).

    HumansExploratory age-stratified adjusted analysis; without baseline cardiovascular disease

    Thyroid antibodies linked to heart risk in younger adults · Journal of translational autoimmunity · 22 Sep 2026

Incident cardiovascular disease →

Latest

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Journal of Translational AutoimmunityHumans

Thyroid antibodies linked to heart risk in younger adults

Across 4,825 adults followed for 14.8 years on average, thyroid antibodies were linked to cardiovascular risk in participants under 40 but not in…Across 4,825 adults followed for 14.8 years on average, thyroid antibodies were linked to cardiovascular risk in participants under 40 but not in those aged 40 and older.