Thrombus weight

1. PAI-1 sirna-lipid nanoparticles decrease thrombus weight in mice.

   “siPAI-1 decreased thrombus weight after complete ligation of the inferior vena cava (IVC) in young and aged mice”

   Animalsafter complete ligation of the inferior vena cava (IVC)

   Silencing of PAI-1 using siRNA-lipid nanoparticles reduces thrombosis and prolongs life span in murine models

   Blood·26 Jan 2026

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