THP-1 cell adhesion

1. Aged serum increases THP-1 cell adhesion in human cells.

   “The combination of aged serum and APP/PSEN1 mutations also resulted in an increase in adhesion of THP-1 neutrophil-like cells, and an increase in sprout length in an angiogenesis assay.”

   Cellswith APP/PSEN1 mutationsbrain microvascular endothelial cells

   Mutations associated with Alzheimer's disease and aged serum synergistically elicit blood-brain barrier dysfunction in a tissue-engineered model

   Fluids and barriers of the CNS·16 Feb 2026

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