Tau PET signal

1. Between-utterance pause duration is associated with tau PET signal in humans (Beta: 0.322, p <0.001).

   “Longer between‐utterance pause duration was positively associated with higher Tau burden in IP (Beta:0.322, p <0.001)”

   Humansinferior parietal cortexn = 238

   Validating Digital Linguistic Features as Potential Biomarkers of Alzheimer's Disease

   AAIC 2025 abstract·24 Dec 2025

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1. Yngve score is associated with tau PET signal in humans (Beta: -0.168, p = 0.02).

   “Reduced syntactic complexity (i.e., lower Yngve_avg scores) were associated with higher Tau burden in IP (Beta:‐0.168, p = 0.02)”

   Humansinferior parietal cortexn = 238

   Validating Digital Linguistic Features as Potential Biomarkers of Alzheimer's Disease

   AAIC 2025 abstract·24 Dec 2025

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1. Idea density is associated with tau PET signal in humans (Beta: -0.148, p = 0.03).

   “lower ideaDensity) was associated with amyloid positivity (Beta: ‐0.542, p = 0.03) and higher Tau burden in entorhinal (Beta:‐0.148, p = 0.03)”

   Humansentorhinal cortexn = 238

   Validating Digital Linguistic Features as Potential Biomarkers of Alzheimer's Disease

   AAIC 2025 abstract·24 Dec 2025

More on Idea density