T2 and T2* relaxation times

Biomarker

2 findings

Associations

2

GAG and water content

upin O. aries1

1 study
  1. T2 and T2* relaxation times are associated with GAG and water content in O. aries.

    “and positively correlated with GAG and water content.”

    AnimalsEx vivo ovine thoracolumbar spine segmentsnucleus pulposusn = 10

    Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI, Radiological, Histological, Biochemical, and Biomechanical Assessments

    JOR spine17 Mar 2026

More on GAG and water content

Histological disc degeneration

downin O. aries1

1 study
  1. T2 and T2* relaxation times are associated with histological disc degeneration in O. aries.

    “T2 and T2* values in the nucleus pulposus (NP) were negatively correlated with age, Pfirrmann grade, and histological degeneration”

    AnimalsEx vivo ovine thoracolumbar spine segmentsnucleus pulposusn = 10

    Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI, Radiological, Histological, Biochemical, and Biomechanical Assessments

    JOR spine17 Mar 2026