Substantia nigra free water
Biomarker1 paper1 finding
- Humans1
Associations
1Phenoconversion to clinically manifest synucleinopathy
upin humans1HR 1.54
1 study
Phenoconversion to clinically manifest synucleinopathy
upin humans1HR 1.54
Substantia nigra free water raises the risk of phenoconversion to clinically manifest synucleinopathy in humans (HR 1.54, 95% CI 1.06-2.24).
Humansisolated REM sleep behavior disorder
Nigro-striatal deficits capture phenoconversion risk in isolated REM sleep behavior disorder · medRxiv · 31 Aug 2026 · Preprint