Structural-decoupling index

1. Amyloid-beta increases structural-decoupling index in humans.

   “Higher amyloid burden was associated with higher SDI at the global (Table 2; Figure 1g) and network‐levels”

   Humanswithout dementia

   Brain structural‐functional coupling is differentially affected by age, sex, and amyloid burden in older individuals without dementia

   AAIC 2025 abstract·25 Dec 2025

More on Amyloid-beta

1. Male sex is associated with structural-decoupling index in humans.

   “Males exhibited lower SDI at both global (Table 2) and network‐level (Figure 1e).”

   Humanswithout dementia

   Brain structural‐functional coupling is differentially affected by age, sex, and amyloid burden in older individuals without dementia

   AAIC 2025 abstract·25 Dec 2025