There are 2 papers on sleep-time relative systolic blood pressure decline in aging research: 2 observational studies in people.
2 papers study it2 findings
2 new papers in 30 daysSee all 2 papers on sleep-time relative systolic blood pressure decline
“baseline enhanced sleep-time relative SBP decline most strongly predicted protection against it (HRadjusted=0.75 (0.67, 0.83); p<0.001]”
- Humans2
Associations
2Progression toward end-stage kidney disease or a major cardiovascular event
downin humans1HR 0.74
1 study
Progression toward end-stage kidney disease or a major cardiovascular event
downin humans1HR 0.74
Sleep-time relative systolic blood pressure decline predicts progression toward end-stage kidney disease or a major cardiovascular event in humans (CKD stages G3b and G4) (HR 0.74, 95% CI 0.59–0.93 per 1 SD elevation).
“1 SD elevation in SBP sleep-time relative decline, indicating an increase in SBP dipping, was associated with lower hazards (HR 0.74, 95%CI 0.59, 0.93).”
HumansCKD stages G3b and G4Median follow-up of 2.31 yearsBoth; 66.7% malesn = 180
AHA Scientific Sessions 2026 abstract
Composite cardiovascular events
downin humans1HR 0.75
1 study
Composite cardiovascular events
downin humans1HR 0.75
Sleep-time relative systolic blood pressure decline predicts composite cardiovascular events in humans (Spanish hypertensives with obstructive sleep apnea; adjusted Cox analysis) (Adjusted HR 0.75 (0.67, 0.83)).
“baseline enhanced sleep-time relative SBP decline most strongly predicted protection against it (HRadjusted=0.75 (0.67, 0.83); p<0.001]”
HumansSpanish hypertensives with obstructive sleep apnea; adjusted Cox analysis5.1-year median follow-up79.5% malesn = 2,065
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