Simplified 4-item frailty score
Biomarker1 paper3 findings
- Humans1
Effects
1European System for Cardiac Operative Risk Evaluation II
upin humans1
1 study
European System for Cardiac Operative Risk Evaluation II
upin humans1
Simplified 4-item frailty score improves European System for Cardiac Operative Risk Evaluation II in humans (C-statistic 0.715 vs 0.668).
Humanssevere valvular heart diseasen = 2,147
Prevalence and Prognostic Significance of Frailty in Elderly Patients With Severe Valvular Heart Diseases · JACC. Advances · 28 Aug 2026
Associations
2All-cause death and heart failure hospitalization
upin humans1HR 1.53
1 study
All-cause death and heart failure hospitalization
upin humans1HR 1.53
Simplified 4-item frailty score raises the risk of all-cause death and heart failure hospitalization in humans (adjusted HR 1.53 (95% CI 1.32-1.77)).
Humanssevere valvular heart disease1-yearn = 2,147
Prevalence and Prognostic Significance of Frailty in Elderly Patients With Severe Valvular Heart Diseases · JACC. Advances · 28 Aug 2026
Mortality
upin humans1HR 1.5
1 study
Mortality
upin humans1HR 1.5
Simplified 4-item frailty score raises the risk of mortality in humans (adjusted HR 1.50 (95% CI 1.25-1.81)).
Humanssevere valvular heart disease1-yearn = 2,147
Prevalence and Prognostic Significance of Frailty in Elderly Patients With Severe Valvular Heart Diseases · JACC. Advances · 28 Aug 2026