Sialic acid

1 paper

Animals1

Funding

1 grant since 2023

National Institute on AgingUS$504.3k

Sialic Acid Modulation of HIV-associated Chronic Inflammaging
National Institute on AgingWistar InstituteUS$504.3k2019–2024

Latest

3 in 12 months

Molecular and Cellular Endocrinology4 Aug

Hepatic Neu1 deficiency drives metabolic dysregulation via GCGR desialylation-dependent cAMP-PKA signaling and inflammatory response in old mice

Experiments in micecAMP signalling

International Immunopharmacology26 Mar

Dietary N-acetylneuraminic acid maintains intestinal homeostasis and protects against aging- and inflammation-associated colonic dysfunction

Experiments in miceGut and microbiome

Gut Microbes10 Feb

Sialic acid-responsive Parabacteroides is linked to gut barrier integrity in older adults

Study in peopleMechanisms

Rejuvenation Research12 Jun

Acarbose Mitigates Age-Dependent Alterations in Erythrocyte Membrane Transporters During Aging in Rats

Experiments in ratsInterventions

PNAS7 Jul

Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1

Experiments in human cellsKL