Severe enlarged basal ganglia perivascular spaces

Biomarker

1 paper1 finding

Human trial1

Effects

Incident hemorrhagic lesions

no changein humans1HR 0.87

1 study

Severe enlarged basal ganglia perivascular spaces have no effect on incident hemorrhagic lesions in humans (Adjusted HR 0.87, 95% CI 0.35–2.18; p = 0.77).
HumansAmyloid-positive, cognitively unimpaired, hemorrhage-free older adultsbrainMedian follow-up 5.1 years61.3% femalesn = 932
Severely enlarged brain vessel spaces predicted bleeding lesions
Annals of neurology9 Oct 2026

Latest

1 in 12 months

Annals of Neurology2 h

Severely enlarged brain vessel spaces predicted bleeding lesions

Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.Over a median 5.1 years, bleeding-related lesions appeared in 33.7% of participants with severe enlargement versus 13.6% without severe enlargement.

Trial in 932 peopleBiomarkers

Paper

Severe enlarged basal ganglia perivascular spaces

Effects

Latest

Severely enlarged brain vessel spaces predicted bleeding lesions

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