Sema3A/NRP1 ratio

Biomarker1 paper1 finding

Humans1

Interventions

1

SGLT2 inhibitors

upin humans1Low certainty

1 study

SGLT2 inhibitors increase Sema3A/NRP1 ratio in humans (0.14 vs. 0.12; p = 0.006).
Humanspostmenopausal women with type 2 diabetes
SGLT2 Inhibitors Are Associated With Suppression of the Sema3A/NRP1/Plexin-A1 Signaling Axis in Postmenopausal Women With Type 2 Diabetes: Evidence From Propensity Score-Matched Analysis · Journal of diabetes · 27 Aug 2026

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Journal of DiabetesHumans27 Aug

SGLT2 Inhibitors Are Associated With Suppression of the Sema3A/NRP1/Plexin-A1 Signaling Axis in Postmenopausal Women With Type 2 Diabetes: Evidence From Propensity Score-Matched Analysis

SGLT2 inhibitors