SCN-2

SCN-2 is associated with cognitive impairment in humans (ρ = 0.154, p < 0.007).

“ρ = 0.154 for cognitive domain, p < 0.007 by Bonferroni-correction”

Humansn = 1,193

Cerebellar and cerebral contributions to dual physical-cognitive impairment in middle-aged and older adults: Potential biomarkers and therapeutic targets for healthy aging

NeuroImage·19 Dec 2025

SCN-2 is associated with physical impairment in humans (ρ = 0.083, p < 0.007).

“SCN-2, predominantly located in the posterior lobe (63% in lobule VI, 10% in Crus I), showed significant association with dual-domain impairment (ρ = 0.083 for physical domain”

Humansn = 1,193

Cerebellar and cerebral contributions to dual physical-cognitive impairment in middle-aged and older adults: Potential biomarkers and therapeutic targets for healthy aging

NeuroImage·19 Dec 2025