What does the research say about sarcopenic obesity index?

Sarcopenic obesity index

There are 2 papers on sarcopenic obesity index in aging research: 1 trial and 1 observational study in people. The newest story, Nov 9, 2026: “Chest muscle and weight index linked to heart failure risk”.

Biomarker

2 papers study it1 more mentions it4 findings

See all 3 papers on sarcopenic obesity index

“A higher sarcopenic obesity index was associated with adverse cardiac remodeling, and with increased risk of incident heart failure (HR: 1.31; 95% CI: 1.16-1.49)”

Imaging-Derived Sarcopenic Obesity and Cardiovascular Outcomes: Insights Into Heart Failure Risk and Muscle BiologyJournal of the American College of Cardiology2026doi:10.1016/j.jacc.2026.05.022

Human trial1
Humans1

Interventions

Resistance training

upin humans1

1 study

Resistance training improves sarcopenic obesity index in humans (compared with control group, 24-week program).
“the SO index was also significantly improved in the EG (P<0.01)”
Human trialcompared with control group, 24-week programthree times per week24 weeksfemalesn = 69
Effects of resistance training on sarcopenic obesity index in older women: A randomized controlled trial
Archives of gerontology and geriatricsMar 31, 2016

Associations

Mortality

upin humans1HR 1.37

1 study

Sarcopenic obesity index is linked with a higher risk of mortality in humans (HR 1.37 (95% CI 1.26–1.49)).
“increased risk of incident heart failure (HR: 1.31; 95% CI: 1.16-1.49), cardiovascular death (HR: 1.51; 95% CI: 1.25-1.81), and all-cause mortality (HR: 1.37; 95% CI: 1.26-1.49)”
Humans
Chest muscle and weight index linked to heart failure risk
Journal of the American College of CardiologyJul 1, 2026

Cardiovascular death

upin humans1HR 1.51

1 study

Sarcopenic obesity index is linked with a higher risk of cardiovascular death in humans (HR 1.51 (95% CI 1.25–1.81)).
“increased risk of incident heart failure (HR: 1.31; 95% CI: 1.16-1.49), cardiovascular death (HR: 1.51; 95% CI: 1.25-1.81), and all-cause mortality (HR: 1.37; 95% CI: 1.26-1.49)”
Humans
Chest muscle and weight index linked to heart failure risk
Journal of the American College of CardiologyJul 1, 2026

Heart failure

upin humans1HR 1.31

1 study

Sarcopenic obesity index is linked with a higher risk of heart failure in humans (HR 1.31 (95% CI 1.16–1.49)).
“A higher sarcopenic obesity index was associated with adverse cardiac remodeling, and with increased risk of incident heart failure (HR: 1.31; 95% CI: 1.16-1.49)”
Humans
Chest muscle and weight index linked to heart failure risk
Journal of the American College of CardiologyJul 1, 2026

Latest

1 paper in 12 months

Journal of the American College of CardiologyJul 1

Chest muscle and weight index linked to heart failure risk

A higher index of excess fat and low muscle mass was associated with heart failure, with a hazard ratio of 1.31.A higher index of excess fat and low muscle mass was associated with heart failure, with a hazard ratio of 1.31.

Cohort · 55,768 peopleHeart failure