Red-flag composite

1. Red-flag composite is associated with adenocarcinoma in humans.

   “Red-flag positivity (≥2 of four features) increased from 5.2% to 32.7% and enriched for adenocarcinoma, although positive predictive values were imprecise and non-monotonic.”

   Humansexploratory analysis; red-flag positivity defined as ≥2 of four featurescolorectaln = 291

   Age-stratified gradients of colorectal neoplasia and an exploratory endoscopic red-flag composite in a lesion-confirmed screening colonoscopy cohort

   Frontiers in oncology·Oct 2, 2026

More on Adenocarcinoma