Radscore

There are 3 papers on radscore in aging research: 2 observational studies in people.

Biomarker

3 papers study it3 more mention it7 findings

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“Radiomics score (Radscore) (adjusted risk ratio (aHR) = 12.04; 95% confidence interval (CI): 5.88–24.64) was independently associated with VFs in T2DM patients.”
A CT-based radiomic model for predicting vertebral fractures in older patients with type 2 diabetes mellitus: A longitudinal studyJournal of endocrinological investigation2025doi:10.1007/s40618-025-02627-z
  • Humans2
  • In silico1

Associations

7

Incident major osteoporotic fracture

upin humans1

1 study
  1. Radscore predicts incident major osteoporotic fracture in humans (type 2 diabetes mellitus) (AUC 0.739 (95% CI: 0.676-0.803)).

    “AUCs for predicting incident clinical vertebral fractures, hip fractures, and MOFs were 0.774 (95% CI: 0.686-0.862), 0.759 (95% CI: 0.645-0.873), and 0.739 (95% CI: 0.676-0.803), respectively.”

    Humanstype 2 diabetes mellitus5-year follow-up

    DXA based radiomics scoring: a novel approach for fragility fracture risk assessment in elderly type 2 diabetes patients

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

More on Incident major osteoporotic fracture

Incident hip fractures

upin humans1

1 study
  1. Radscore predicts incident hip fractures in humans (type 2 diabetes mellitus) (AUC 0.759 (95% CI: 0.645-0.873)).

    “AUCs for predicting incident clinical vertebral fractures, hip fractures, and MOFs were 0.774 (95% CI: 0.686-0.862), 0.759 (95% CI: 0.645-0.873), and 0.739 (95% CI: 0.676-0.803), respectively.”

    Humanstype 2 diabetes mellitus5-year follow-up

    DXA based radiomics scoring: a novel approach for fragility fracture risk assessment in elderly type 2 diabetes patients

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

More on Incident hip fractures

Incident clinical vertebral fracture

upin humans1

1 study
  1. Radscore predicts incident clinical vertebral fracture in humans (type 2 diabetes mellitus) (AUC 0.774 (95% CI: 0.686-0.862)).

    “In the validation set, AUCs for predicting incident clinical vertebral fractures, hip fractures, and MOFs were 0.774 (95% CI: 0.686-0.862), 0.759 (95% CI: 0.645-0.873), and 0.739 (95% CI: 0.676-0.803), respectively.”

    Humanstype 2 diabetes mellitus5-year follow-up

    DXA based radiomics scoring: a novel approach for fragility fracture risk assessment in elderly type 2 diabetes patients

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA

More on Incident clinical vertebral fracture

Vertebral fracture

upin humans1

1 study
  1. Radscore predicts vertebral fracture in humans (type 2 diabetes mellitus) (aHR = 12.04, 95% CI: 5.88–24.64).

    “Radiomics score (Radscore) (adjusted risk ratio (aHR) = 12.04; 95% confidence interval (CI): 5.88–24.64) was independently associated with VFs in T2DM patients.”

    Humanstype 2 diabetes mellitus

    A CT-based radiomic model for predicting vertebral fractures in older patients with type 2 diabetes mellitus: A longitudinal study

    Journal of endocrinological investigation

More on Vertebral fracture

Mild cognitive impairment progression

upin humans1

1 study
  1. Radscore predicts mild cognitive impairment progression in humans (MCI subjects followed for 48 months) (P = .002).

    “The probability to progression of low and high heterogeneity groups had a significant difference (P = .002).”

    HumansMCI subjects followed for 48 months48 monthsn = 104

    Pattern of heterogeneity in normal brain ageing: screening for mild cognitive impairment and its risk of progression with a radiomics model

    Age and ageing

Mild cognitive impairment

upin humans1

1 study
  1. Mild cognitive impairment is associated with radscore in humans (matched with cognitively normal subjects) (P < .001).

    “The radscore of MCI subjects was significantly higher than that of matched CN subjects (P < .001).”

    Humansmatched with cognitively normal subjects

    Pattern of heterogeneity in normal brain ageing: screening for mild cognitive impairment and its risk of progression with a radiomics model

    Age and ageing

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Age

upin humans1

1 study
  1. Age is associated with radscore in cognitively normal subjects (r = 0.501, P < .001).

    “There was a significantly positive correlation between age and radscore of CN subjects (r = 0.501; P < .001).”

    Humansin cognitively normal subjects

    Pattern of heterogeneity in normal brain ageing: screening for mild cognitive impairment and its risk of progression with a radiomics model

    Age and ageing

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