Protection Index

1. Protection Index has no effect on negative frailty transitions in humans.

   “but showed no significant effect among those with existing frailty.”

   Humansindividuals with existing frailty2 years

   A National Follow-up Study on the Effect of Health Protective Factors on Frailty Transition among Older Adults in China

   Biomedical and environmental sciences : BES·20 Mar 2026

1. Protection Index is associated with negative frailty transitions in humans (OR = 0.989).

   “A higher PI was associated with a lower risk of negative transitions among robust and prefrail individuals ( OR = 0.989, 0.981, both P < 0.05)”

   Humansrobust individuals2 years

   A National Follow-up Study on the Effect of Health Protective Factors on Frailty Transition among Older Adults in China

   Biomedical and environmental sciences : BES·20 Mar 2026

1. Protection Index is associated with frailty index in humans (r = -0.349).

   “The PI was moderately negatively correlated with the FI ( r = -0.349, P < 0.001).”

   Humansolder adults in Chinan = 9,093

   A National Follow-up Study on the Effect of Health Protective Factors on Frailty Transition among Older Adults in China

   Biomedical and environmental sciences : BES·20 Mar 2026

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